Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 3/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30675982 | 1.00 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL30786303 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL7019052 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL28930119 | 0.81 | BCAT2 (0.51) | PARP1PARP2BCAT2 | |
| SCHEMBL11817017 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL19283593 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL7023563 | 0.76 | AGTR1 (0.59) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4772912 | 0.73 | CSNK1A1 (0.50) | ALDH1A1PARP1BCAT2CSNK1A1TYRO3 | |
| SCHEMBL210767 | 0.73 | BCAT2 (0.74) | ALDH1A1L3MBTL1GAAPARP1BCAT2 | |
| SCHEMBL30514077 | 0.73 | BCAT2 (0.74) | ALDH1A1L3MBTL1GAAPARP1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209476-A | Antifolate linker-drug and antibody-drug conjugates | 拜奥迪斯私人有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-114173772-A | Inhibitors of CD40-CD154 binding | 托尼克斯医药控股公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-1356977-A | Glucagon antagonists/inverse agonists | NOVO NORDISK AS (DK) | 2002-07-03 | — | — | CN | disclosed |
| EP-1183229-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |