Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 10/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451645 | 0.74 | KCNN4 (0.45) | KMT2AMAPTKCNN4HTTPTPN1 | |
| SCHEMBL27568720 | 0.72 | KCNN4 (0.44) | KMT2AMAPTKCNN4HTTPTPN1 | |
| Hydrochloric Acid SCHEMBL29145555 | 0.72 | KCNN4 (0.44) | KMT2AMAPTKCNN4HTTPTPN1 | |
| SCHEMBL29095960 | 0.72 | KCNN4 (0.44) | KMT2AMAPTKCNN4HTTPTPN1 | |
| SCHEMBL27702859 | 0.71 | MAPT (0.59) | KMT2AMAPTKCNN4HTTKCNE1 | |
| SCHEMBL8583194 | 0.71 | KCNN4 (0.42) | KMT2AMAPTKCNN4HTTPTPN1 | |
| SCHEMBL6016877 | 0.70 | MAPT (0.63) | KMT2AMAPTKCNN4HTTALDH1A1 | |
| SCHEMBL28049560 | 0.70 | CHRM3 (0.46) | KMT2AMAPTKCNN4ALDH1A1 | |
| SCHEMBL29019887 | 0.70 | MAPT (0.52) | KMT2AMAPTKCNN4HTTKCNE1 | |
| SCHEMBL5560839 | 0.69 | MAPT (0.47) | KMT2AMAPTKCNN4HTTKCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924551-A2 | ORGANIC COMPOUNDS | Novartis Pharma AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025709-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-03-08 | — | — | WO | disclosed |