Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778011 | 0.87 | CA2 (0.60) | PPARGMAPTALDH1A1NPSR1AKT1 | |
| SCHEMBL4845571 | 0.85 | PPARG (0.49) | PPARGMAPTALDH1A1NPSR1MAOA | |
| SCHEMBL98544 | 0.77 | ALDH1A1 (0.49) | PPARGMAPTALDH1A1NPSR1MAOA | |
| SCHEMBL13846702 | 0.76 | PPARG (0.59) | PPARGMAPTALDH1A1NPSR1MAOA | |
| SCHEMBL9570559 | 0.76 | MAPT (0.83) | PPARGMAPTALDH1A1NPSR1MAOA | |
| SCHEMBL166570 | 0.75 | PPARG (0.74) | PPARGMAPTALDH1A1NPSR1MAOA | |
| SCHEMBL4089698 | 0.75 | ALDH1A1 (0.50) | PPARGMAPTALDH1A1NPSR1MAOA | |
| SCHEMBL4778234 | 0.74 | KDM4E (0.53) | PPARGMAPTALDH1A1NPSR1MAOA | |
| SCHEMBL13846727 | 0.74 | PPARG (0.47) | PPARGMAPTFFAR1 | |
| SCHEMBL6866703 | 0.73 | PPARG (0.71) | PPARGMAPTALDH1A1NPSR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |