Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932687 | 0.81 | IDO1 (0.54) | ALDH1A1KDM4EKMT2AMEN1PPARG | |
| SCHEMBL4773524 | 0.77 | PPARG (0.53) | ALDH1A1CA2PPARGMAPTMAOA | |
| SCHEMBL9570635 | 0.76 | MAPT (0.53) | ALDH1A1KDM4ECA2PPARGKCNH2 | |
| SCHEMBL13846714 | 0.76 | PARP1 (0.46) | ALDH1A1KMT2AMEN1CA2PPARG | |
| SCHEMBL4089698 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2AMEN1ALOX15 | |
| SCHEMBL96600 | 0.76 | PPARG (0.48) | ALDH1A1KDM4ECA2PPARGSMN1; SMN2 | |
| SCHEMBL13846727 | 0.75 | PPARG (0.47) | PPARGMAPT | |
| SCHEMBL4089575 | 0.74 | MAPT (0.50) | ALDH1A1KDM4EKMT2AMEN1CA2 | |
| SCHEMBL30430848 | 0.74 | ALDH1A1 (0.67) | ALDH1A1KDM4EKMT2AMEN1ALOX15 | |
| SCHEMBL8687818 | 0.74 | MAPT (0.44) | ALDH1A1KDM4ECA2PPARGKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | claimed |