Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.81 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.77 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15336407 | 0.91 | HDAC1 (0.87) | MMP3HDAC1HDAC2TSHRKMT2A | |
| SCHEMBL7044763 | 0.90 | MMP3 (1.00) | MMP3HDAC1HDAC2CYP1A2CYP3A4 | |
| SCHEMBL19789098 | 0.89 | HDAC1 (0.97) | MMP3HDAC1HDAC2KMT2AHDAC3 | |
| SCHEMBL7047876 | 0.85 | MMP3 (0.75) | MMP3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL26345693 | 0.83 | CYP1A2 (0.67) | MMP3HDAC1HDAC2CYP1A2CYP3A4 | |
| SCHEMBL10588204 | 0.83 | CYP1A2 (0.67) | MMP3HDAC1HDAC2CYP1A2CYP3A4 | |
| SCHEMBL4412374 | 0.83 | CYP1A2 (0.67) | MMP3HDAC1HDAC2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7190843 | 0.81 | CYP1A2 (0.65) | MMP3HDAC1HDAC2CYP1A2CYP3A4 | |
| SCHEMBL7044856 | 0.81 | HDAC1 (0.88) | MMP3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL25365255 | 0.80 | TSHR (0.69) | MMP3HDAC1HDAC2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115605-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-03 | — | — | US | claimed |
| US-20040192719-A1 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-09-30 | — | — | US | claimed |
| US-20040053932-A1 | Peptide deformylase inhibtors | GLAXOSMITHKLINE LLC | 2004-03-18 | — | — | US | claimed |
| EP-1283711-B1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2008-03-19 | — | — | EP | disclosed |
| US-7115605-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-03 | — | — | US | disclosed |
| WO-2001085170-A9 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-01-26 | — | — | WO | disclosed |
| US-6806369-B2 | N-FORMYL-N-HYDROXY-2-(5-ISOQUINOLINOXY)ETHYLAMINE ANTI-BACTERIAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2004-10-19 | — | — | US | disclosed |
| US-20040192719-A1 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-09-30 | — | — | US | disclosed |
| US-20040053932-A1 | Peptide deformylase inhibtors | GLAXOSMITHKLINE LLC | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053932-A1 | Peptide deformylase inhibtors | PDF, VIP, SPPL2B | MMP3 1461/4885HDAC1 3252/4885HDAC2 3662/4885 |
| US-20040192719-A1 | Peptide deformylase inhibitors | PDF, PEPD, DPEP1 | MMP3 1467/4885HDAC1 3488/4885HDAC2 3549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.