Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777741 | 0.83 | PTGER4 (0.48) | POLBHTTLMNAALDH1A1MAPT | |
| SCHEMBL16300503 | 0.79 | POLB (0.61) | POLBHTTLMNAALDH1A1MAPT | |
| SCHEMBL6721051 | 0.76 | POLB (0.57) | POLBHTTLMNAALDH1A1MAPT | |
| SCHEMBL6720986 | 0.75 | POLB (0.55) | POLBHTTLMNAALDH1A1MAPT | |
| SCHEMBL30344008 | 0.73 | POLB (0.64) | POLBHTTLMNAALDH1A1MAPT | |
| SCHEMBL1180653 | 0.73 | POLB (0.64) | POLBHTTLMNAALDH1A1MAPT | |
| SCHEMBL592694 | 0.71 | POLB (0.61) | POLBHTTLMNAALDH1A1MAPT | |
| SCHEMBL10879830 | 0.71 | POLB (0.61) | POLBHTTLMNAALDH1A1MAPT | |
| SCHEMBL30165646 | 0.71 | POLB (0.61) | POLBHTTLMNAALDH1A1MAPT | |
| SCHEMBL153365 | 0.71 | POLB (1.00) | POLBHTTLMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |