Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | NNMT | P40261 | 2/20 | 0.37 |
| ▸ | AKT1S1 | Q96B36 | 4/20 | 0.34 |
| ▸ | AOC1 | P19801 | 3/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4101024 | 0.98 | LOXL2 (0.38) | LOXL2NNMTAKT1S1AOC1AOC3 | |
| Hydrochloric Acid SCHEMBL3149777 | 0.98 | LOXL2 (0.38) | LOXL2NNMTAKT1S1AOC1AOC3 | |
| Hydrochloric Acid SCHEMBL4974636 | 0.98 | LOXL2 (0.38) | LOXL2NNMTAKT1S1AOC1AOC3 | |
| SCHEMBL11987587 | 0.81 | HTR2C (0.43) | NNMTPARP1 | |
| SCHEMBL13138806 | 0.75 | PARP1 (0.42) | NNMTAKT1S1PARP1 | |
| SCHEMBL14420679 | 0.74 | ADRB2 (0.41) | LOXL2 | |
| SCHEMBL797186 | 0.71 | UHRF1 (0.41) | NNMTAKT1S1PARP1 | |
| SCHEMBL580706 | 0.71 | NNMT (0.37) | NNMT | |
| SCHEMBL13991574 | 0.71 | PARP10 (0.42) | NNMT | |
| SCHEMBL795352 | 0.71 | NNMT (0.44) | NNMTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562933-B1 | SUBSTITUTED AMINE DERIVATIVES AND METHODS OF USE IN THE TREATMENT OF ANGIOGENESIS RELATED DISORDERS | AMGEN INC (US) | 2008-03-19 | — | — | EP | disclosed |