Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 3/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11365473 | 0.81 | KCNH2 (0.47) | EYA3SLC22A12CYP2C19CYP2C9MEN1 | |
| SCHEMBL28131940 | 0.81 | TEAD1 (0.51) | MEN1LMNAKMT2AMAPTALDH1A1 | |
| SCHEMBL5860509 | 0.79 | EYA3 (0.49) | EYA3SLC22A12CYP2C19CYP2C9MEN1 | |
| SCHEMBL13348986 | 0.78 | ABCB1 (0.46) | EYA3SLC22A12CYP2C19CYP2C9MEN1 | |
| Formamide SCHEMBL23320479 | 0.78 | EYA3 (0.46) | EYA3SLC22A12CYP2C19CYP2C9MEN1 | |
| Oxalic Acid SCHEMBL28849573 | 0.77 | ALDH1A1 (0.49) | MEN1LMNAKMT2AMAPTALDH1A1 | |
| SCHEMBL8788305 | 0.76 | EYA3 (0.51) | EYA3SLC22A12CYP2C19CYP2C9MEN1 | |
| Sulfuric Acid SCHEMBL28171448 | 0.76 | KMT2A (0.47) | LMNAKMT2AMAPTALDH1A1POLB | |
| SCHEMBL1252238 | 0.76 | PTPN1 (0.47) | EYA3SLC22A12CYP2C19CYP2C9MEN1 | |
| SCHEMBL4095186 | 0.75 | PLK1 (0.46) | EYA3SLC22A12CYP2C19CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973902-A2 | 3-HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | Affinium Pharmaceuticals, Inc. (CA) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007067416-A2 | HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2007-06-14 | — | — | WO | disclosed |