SCHEMBL4774186

SCHEMBL4774186

COC1(OC)C[C@@H](O)CC(=O)O1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30818409 0.67 TYR (0.35) ALDH1A1LMNA
SCHEMBL13292092 0.67 HSD11B1 (0.35) LMNA
SCHEMBL13292098 0.65 TSHR (0.36) ALDH1A1LMNA
SCHEMBL28562678 0.64 PRKCA (0.32) LMNA
SCHEMBL9420122 0.64 KDM1A (0.30)
SCHEMBL9420128 0.64 KDM1A (0.30)
SCHEMBL31680371 0.61
SCHEMBL5345898 0.60
SCHEMBL5046206 0.59
SCHEMBL3912478 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1978020-A1 Processes for the preparation of statins, particularly rosuvastatin, and intermediates for the preparation thereof LEK Pharmaceuticals D.D. (SI) 2008-10-08 EP disclosed