Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 10/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829929 | 0.85 | NOTUM (0.48) | DGAT1 | |
| SCHEMBL408898 | 0.83 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL408273 | 0.83 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL6178854 | 0.82 | DGAT1 (0.51) | DGAT1NPSR1 | |
| SCHEMBL14319143 | 0.82 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL407419 | 0.82 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL6603948 | 0.81 | AR (0.43) | AR | |
| SCHEMBL4293751 | 0.80 | ALDH1A1 (0.54) | DGAT1NPSR1 | |
| SCHEMBL29333627 | 0.79 | ALDH1A1 (0.42) | NPSR1 | |
| SCHEMBL6741238 | 0.78 | L3MBTL1 (0.57) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157273-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | disclosed |