⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1138478 | 0.97 | ACHE (0.47) | — | |
| Iodide SCHEMBL10814411 | 0.97 | ACHE (0.47) | — | |
| Tetrahydrofuran SCHEMBL28711110 | 0.82 | ALDH1A1 (0.33) | — | |
| SCHEMBL464793 | 0.73 | ACHE (0.57) | — | |
| P-Xylene SCHEMBL11553864 | 0.71 | ACHE (0.80) | — | |
| SCHEMBL2315951 | 0.71 | — | — | |
| SCHEMBL7064307 | 0.71 | ACHE (0.53) | — | |
| P-Xylene SCHEMBL460348 | 0.71 | ACHE (1.00) | — | |
| P-Xylene SCHEMBL11772917 | 0.71 | ACHE (1.00) | — | |
| P-Xylene SCHEMBL771 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554206-B | Synthetic taxol resistant cell strain H460TaxRMethods of inhibiting | 北京化工大学 | 2025-03-25 | — | — | CN | claimed |
| CN-118063354-B | Synthesis method of high-purity p-toluenesulfonyl chloride | 寿光诺盟化工有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118063354-A | Synthesis method of high-purity p-toluenesulfonyl chloride | 寿光诺盟化工有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117619333-A | Continuous reaction system for continuously producing sartan biphenyl and continuous method for preparing sartan biphenyl | 天津凯莱英医药科技发展有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-116554206-A | Synthetic taxol resistant cell strain H460 TaxR Methods of inhibiting | 北京化工大学 | 2023-08-08 | — | — | CN | claimed |
| CN-115611769-A | Method and device for synthesizing sartanbiphenyl by continuous flow | 赛诺威(厦门)科技有限公司 | 2023-01-17 | — | — | CN | claimed |
| EP-3902793-A1 | CHEMICAL COMPOUND MANUFACTURE, NEW SALT FORM, AND THERAPEUTIC USES THEREOF | Eustralis Pharmaceuticals Limited (Trading as Pressura Neuro) (AU) | 2021-11-03 | — | — | EP | claimed |
| WO-2020132716-A1 | CHEMICAL COMPOUND MANUFACTURE, NEW SALT FORM, AND THERAPEUTIC USES THEREOF | EUSTRALIS PHARMACEUTICALS LIMITED (TRADING AS PRESSURA NEURO) (AU) | 2020-07-02 | — | — | WO | claimed |
| CN-109384712-A | Target the application in NK1 receptor antagonist and its treatment of the Nausea and vomiting caused by chemotherapy | 北京宽厚医药科技有限公司 | 2019-02-26 | — | — | CN | claimed |
| US-8609574-B2 | In situ olefin polymerization catalyst system | PROMERUS LLC (US) | 2013-12-17 | — | — | US | claimed |
| EP-1066248-B1 | METHYL-BIPHENYL DERIVATIVES, PREPARATION METHOD AND USE | SANOFI SYNTHELABO (FR) | 2003-06-18 | — | — | EP | claimed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | claimed |
| US-6417400-B1 | O-(P-TOLYL)-BENZALDIMINE IS REACTED WITH HYDROXYLAMINE SALT TO FORM O-(P-TOLYL)-BENZALDOXIME; O-(P-TOLYL)-BENZONITRILE CHEMICAL INTERMEDIATES FOR DRUGS; OXIMINATION, IMINATION | SANOFI-SYNTHELABO (FR) | 2002-07-09 | — | — | US | claimed |
| US-20020077250-A1 | Process for preparing aryl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-20 | — | — | US | claimed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| US-6194599-B1 | Process for preparing biaryl compounds | CATALYTICA, INC. | 2001-02-27 | — | — | US | claimed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | claimed |
| US-5922898-A | Process for preparing biaryl compounds | CATALYTICA PHARMACEUTICALS, INC. (US) | 1999-07-13 | — | — | US | claimed |
| US-5874606-A | Process for making o-arylbenzonitriles | OCCIDENTAL CHEMICAL CORPORATION (US) | 1999-02-23 | — | — | US | claimed |
| US-4339560-A | Process for polymerizing olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-07-13 | — | — | US | claimed |