Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | ITK | Q08881 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688386 | 0.88 | TSHR (0.54) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL25068790 | 0.86 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5610913 | 0.83 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL14882 | 0.82 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL21117527 | 0.81 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL316981 | 0.81 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2457988 | 0.81 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL20816539 | 0.81 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL474181 | 0.81 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Potassium SCHEMBL29895343 | 0.81 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111228124-B | Rapidly curing and low shrinkage stress photopolymerizable dental composites | 义获嘉伟瓦登特公司 | 2024-04-09 | — | — | CN | claimed |
| US-20230265220-A1 | Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress | IVOCLAR VIVADENT AG (LI) | 2023-08-24 | — | — | US | claimed |
| US-11673980-B2 | Photopolymerizable dental composites with rapid curing and low shrinkage stress | IVOCLAR VIVADENT AG (LI) | 2023-06-13 | — | — | US | claimed |
| CN-111228124-A | Rapid curing and low shrinkage stress photopolymerizable dental composites | 义获嘉伟瓦登特公司 | 2020-06-05 | — | — | CN | claimed |
| US-20200165363-A1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS | IVOCLAR VIVADENT AG (LI) | 2020-05-28 | — | — | US | claimed |
| US-6107365-A | A COPOLYMER OF METHACRYLATE FUNCTIONAL SULFOXIDE, SULFIDE OR SULFONE MONOMERS AND A COMONOMER SELECTED FROM HYDROPHILIC OR HYDROPHOBIC MATERIAL SELECTED FROM ACRYLMIDE, ACRYLATE, METHACRYLATE, SILOXANE, VINYL AND A DERIVATIVE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-08-22 | — | — | US | claimed |
| CN-111228124-B | Rapidly curing and low shrinkage stress photopolymerizable dental composites | 义获嘉伟瓦登特公司 | 2024-04-09 | — | — | CN | disclosed |
| US-20230265220-A1 | Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress | IVOCLAR VIVADENT AG (LI) | 2023-08-24 | — | — | US | disclosed |
| US-20230248000-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF USE | AEQUOR, INC. (US) | 2023-08-10 | — | — | US | disclosed |
| US-11673980-B2 | Photopolymerizable dental composites with rapid curing and low shrinkage stress | IVOCLAR VIVADENT AG (LI) | 2023-06-13 | — | — | US | disclosed |
| CN-111228124-A | Rapid curing and low shrinkage stress photopolymerizable dental composites | 义获嘉伟瓦登特公司 | 2020-06-05 | — | — | CN | disclosed |
| US-20200165363-A1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS | IVOCLAR VIVADENT AG (LI) | 2020-05-28 | — | — | US | disclosed |
| EP-3070138-B1 | ULTRAVIOLET SCATTERING AGENT AND APPLICATION THEREFOR | NISSHINBO HOLDINGS INC (JP) | 2019-01-02 | — | — | EP | disclosed |
| US-20070054123-A1 | Oval-spherical organic polymer particles and method of production | NISSHINBO INDUSTRIES, INC. (JP) | 2007-03-08 | — | — | US | disclosed |
| EP-1721911-A1 | OVAL-SPHERICAL ORGANIC POLYMER PARTICLE AND PROCESS FOR PRODUCING THE SAME | Nisshinbo Industries, Inc. (JP) | 2006-11-15 | — | — | EP | disclosed |
| US-6552103-B1 | Soft contact lenses and biomedical implants | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-04-22 | — | — | US | disclosed |
| EP-1017737-A4 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | UNIV CALIFORNIA (US) | 2002-06-26 | — | — | EP | disclosed |
| US-6107365-A | A COPOLYMER OF METHACRYLATE FUNCTIONAL SULFOXIDE, SULFIDE OR SULFONE MONOMERS AND A COMONOMER SELECTED FROM HYDROPHILIC OR HYDROPHOBIC MATERIAL SELECTED FROM ACRYLMIDE, ACRYLATE, METHACRYLATE, SILOXANE, VINYL AND A DERIVATIVE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-08-22 | — | — | US | disclosed |
| EP-1017737-A1 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | The Regents of the University of California (US) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999011692-A1 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265220-A1 | Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress | MMAB, ALAD, SULT1E1 | TSHR 3592/4885ALDH1A1 355/4885CYP3A4 2303/4885 |
| US-11673980-B2 | Photopolymerizable dental composites with rapid curing and low shrinkage stress | MMAB, ALAD, SULT1E1 | TSHR 3592/4885ALDH1A1 355/4885CYP3A4 2303/4885 |
| US-20200165363-A1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS | MMAB, ALAD, SULT1E1 | TSHR 3592/4885ALDH1A1 355/4885CYP3A4 2303/4885 |
| US-20230248000-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF USE | DDT, PFAS, CASP10 | TSHR 1007/4885ALDH1A1 3276/4885CYP3A4 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.