Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1054599 | 0.90 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| SCHEMBL9611962 | 0.86 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| SCHEMBL19601495 | 0.83 | — | — | |
| SCHEMBL733100 | 0.82 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| SCHEMBL5575152 | 0.80 | LMNA (0.39) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| SCHEMBL7177498 | 0.80 | LMNA (0.39) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| SCHEMBL18161665 | 0.80 | LMNA (0.30) | LMNATSHR | |
| SCHEMBL4874547 | 0.80 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL13318373 | 0.80 | LMNA (0.39) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| SCHEMBL18276 | 0.80 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044518-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2018-02-15 | — | — | US | disclosed |
| US-9815979-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9617423-B2 | Macroinitiator containing hydrophobic segment | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20170051145-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2017-02-23 | — | — | US | disclosed |
| US-9522980-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160194497-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | JOHNSON & JOHNSON VISION CARE (US) | 2016-07-07 | — | — | US | disclosed |
| US-9321890-B2 | Macroinitiator containing hydrophobic segment | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20140296368-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | JOHNSON & JOHNSON VISION CARE (US) | 2014-10-02 | — | — | US | disclosed |
| US-20120283381-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | JOHNSON & JOHNSON VISION CARE, INC. | 2012-11-08 | — | — | US | disclosed |
| US-20110275734-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2011-11-10 | — | — | US | disclosed |
| US-20100331443-A1 | SILICONE HYDROGELS FORMED FROM SYMMETRIC HYDROXYL FUNCTIONALIZED SILOXANES | JOHNSON & JOHNSON VISION CARE, INC. | 2010-12-30 | — | — | US | disclosed |