Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.45 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.45 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780661 | 0.91 | ABCG2 (0.51) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL4778315 | 0.81 | POLB (0.44) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL4778137 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL4776501 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL18409235 | 0.75 | NPC1 (0.68) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL4776212 | 0.74 | KMT2A (0.39) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL4779650 | 0.73 | MAPT (0.46) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL6727635 | 0.73 | RAB9A (0.64) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL4778477 | 0.72 | MEN1 (0.45) | ALDH1A1MAPTKMT2AMEN1POLB | |
| Biphenyl-4-Amine SCHEMBL27950704 | 0.72 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |