Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779144 | 0.89 | MEN1 (0.47) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL4774577 | 0.88 | CNR2 (0.51) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL4774224 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL4774514 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL4780661 | 0.81 | ABCG2 (0.51) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL4778137 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL4776571 | 0.77 | ABCG2 (0.46) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL14302669 | 0.76 | BRAF (0.47) | ALDH1A1PDE5AABCG2F2F7 | |
| SCHEMBL13309932 | 0.71 | HRH4 (0.60) | ALDH1A1PDE5AABCG2 | |
| SCHEMBL18409235 | 0.71 | NPC1 (0.68) | ALDH1A1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |