Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PSD | A5PKW4 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TNFSF10 | P50591 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629172 | 0.80 | MAPT (0.53) | RAB9AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4780673 | 0.74 | CYP11B1 (0.45) | KMT2AMEN1MAPTCYP1A2CYP2C9 | |
| SCHEMBL629576 | 0.70 | MAPT (0.48) | PSDKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL628013 | 0.70 | MEN1 (0.49) | RAB9AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL29769219 | 0.70 | XDH (0.58) | RAB9AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL629287 | 0.69 | MEN1 (0.51) | RAB9APSDKMT2AMEN1MAPT | |
| SCHEMBL1409329 | 0.69 | NPC1 (0.50) | RAB9AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9983363 | 0.68 | ALDH1A1 (0.64) | RAB9AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10559120 | 0.68 | MEN1 (0.62) | RAB9AKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL2117163 | 0.68 | NPC1 (0.49) | RAB9AKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |