Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263369 | 0.81 | HTT (0.54) | TSHRHSD17B10MAPTSMN1; SMN2HPGD | |
| SCHEMBL353828 | 0.79 | CTSD (0.70) | PLK1TSHRHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL17544377 | 0.78 | TAS1R3 (0.61) | PLK1HSD17B10MAPTCTSDMTNR1A | |
| SCHEMBL1534502 | 0.78 | RAB9A (0.61) | PLK1MAPTSMN1; SMN2HPGDTP53 | |
| SCHEMBL5954008 | 0.78 | PLK1 (0.54) | PLK1HSD17B10CTSD | |
| Hydrochloric Acid SCHEMBL7476155 | 0.78 | CTSD (0.68) | PLK1TSHRHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL31650667 | 0.77 | KAT6A (0.58) | PLK1HSD17B10SMN1; SMN2CTSDMTNR1A | |
| SCHEMBL2063675 | 0.77 | CTSD (0.53) | PLK1HSD17B10MAPTSMN1; SMN2CTSD | |
| SCHEMBL10521510 | 0.75 | PLK1 (0.51) | PLK1HSD17B10SMN1; SMN2CTSDMTNR1A | |
| Alcohol SCHEMBL6834845 | 0.75 | CTSD (0.69) | PLK1TSHRHSD17B10MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008431-A2 | HETEROARYL SULFONAMIDES AND CCR2/CCR9 | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | disclosed |