Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594361 | 0.97 | MEN1 (0.68) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL17313725 | 0.94 | MEN1 (0.62) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL7263741 | 0.93 | MEN1 (0.59) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL12126606 | 0.87 | MEN1 (0.57) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL12126612 | 0.86 | MEN1 (0.64) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL15460111 | 0.86 | MEN1 (0.68) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL21229069 | 0.84 | MEN1 (0.56) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL24505004 | 0.83 | MEN1 (0.50) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL13531288 | 0.83 | MEN1 (0.68) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL4074508 | 0.83 | MEN1 (0.48) | MEN1KMT2AKDM4CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110274713-A1 | ANTIGEN-PRESENTING SCAFFOLDS | THE UNIVERSITY OF QUEENSLAND (AU) | 2011-11-10 | — | — | US | disclosed |
| US-20110274713-A1 | ANTIGEN-PRESENTING SCAFFOLDS | THE UNIVERSITY OF QUEENSLAND (AU) | 2011-11-10 | — | — | US | disclosed |
| WO-2010015022-A1 | ANTIGEN-PRESENTING SCAFFOLDS | THE UNIVERSITY OF QUEENSLAND (AU) | 2010-02-11 | — | — | WO | disclosed |
| EP-1020445-B1 | FUSED PYRIDINE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6875761-B2 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. (JP) | 2005-04-05 | — | — | US | disclosed |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. | 2004-10-14 | — | — | US | disclosed |
| US-6790844-B2 | MUSCLE RELAXANTS; ANTISEROTONINE AGENT | EISAI CO., LTD (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020013460-A1 | Condensed pyridine compound | EISAI CO., LTD | 2002-01-31 | — | — | US | disclosed |
| US-6340759-B1 | ANTISPASMODIC AGENTS | EISAI CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1020445-A1 | FUSED PYRIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013460-A1 | Condensed pyridine compound | MUSK, HTR1A, PAX3 | MEN1 786/4885KMT2A 1240/4885KDM4C 1295/4885 |
| US-20110274713-A1 | ANTIGEN-PRESENTING SCAFFOLDS | CD74, LY96, MICA | MEN1 3636/4885KMT2A 2424/4885KDM4C 1186/4885 |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | MUSK, HTR1A, RYR1 | MEN1 1171/4885KMT2A 1300/4885KDM4C 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.