Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.53 |
| ▸ | CTSS | P25774 | 15/20 | 0.53 |
| ▸ | CTSL | P07711 | 13/20 | 0.53 |
| ▸ | CTSB | P07858 | 10/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775169 | 0.86 | CTSK (0.56) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4129755 | 0.81 | CTSL (0.47) | CTSKCTSSCTSL | |
| SCHEMBL8350075 | 0.79 | CTSK (0.65) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4309572 | 0.78 | CTSK (0.67) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4310706 | 0.78 | CTSK (0.67) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4039064 | 0.78 | CTSK (0.67) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7463893 | 0.75 | CTSK (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4949590 | 0.70 | KMT2A (0.53) | — | |
| SCHEMBL7187462 | 0.70 | CTSK (0.51) | CTSKCTSSCTSLCTSB | |
| SCHEMBL28778928 | 0.69 | TSHR (0.47) | CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940785-A2 | ACYCLIC 1,4-DIAMINES AND USES THEREOF | SmithKline Beecham Corporation (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007030761-A2 | ACYCLIC 1,4-DIAMINES AND USES THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-15 | — | — | WO | disclosed |