Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.53 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 4/20 | 0.41 |
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | CTSH | P09668 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775289 | 1.00 | CTSK (0.53) | CTSKSLC15A1CTSLCTSBDPP4 | |
| SCHEMBL3326210 | 1.00 | CTSK (0.53) | CTSKSLC15A1CTSLCTSBDPP4 | |
| SCHEMBL3326212 | 1.00 | CTSK (0.53) | CTSKSLC15A1CTSLCTSBDPP4 | |
| SCHEMBL6031204 | 0.93 | CTSK (0.59) | CTSKSLC15A1CTSLCTSBDPP4 | |
| SCHEMBL8003112 | 0.93 | CTSK (0.59) | CTSKSLC15A1CTSLCTSBDPP4 | |
| SCHEMBL9572289 | 0.93 | CTSK (0.59) | CTSKSLC15A1CTSLCTSBDPP4 | |
| SCHEMBL4226584 | 0.92 | CTSK (0.43) | CTSKSLC15A1CTSLCTSBDPP4 | |
| SCHEMBL4226580 | 0.92 | CTSK (0.43) | CTSKSLC15A1CTSLCTSBDPP4 | |
| SCHEMBL1783728 | 0.86 | CTSK (0.56) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL14876797 | 0.86 | CTSK (0.56) | CTSKCTSLCTSBCTSHCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994406-A1 | METHODS FOR IDENTIFYING T-CELL EPITOPES ASSOCIATED WITH IMPAIRED PEPTIDE PROCESSING AND APPLICATIONS OF THE IDENTIFIED EPITOPES | Leiden University Medical Center (NL) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007105954-A1 | METHODS FOR IDENTIFYING T-CELL EPITOPES ASSOCIATED WITH IMPAIRED PEPTIDE PROCESSING AND APPLICATIONS OF THE IDENTIFIED EPITOPES | LEIDEN UNIVERSITY MEDICAL CENTER (NL) | 2007-09-20 | — | — | WO | disclosed |