Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | TDO2 | P48775 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477379 | 1.00 | IDO1 (0.54) | IDO1TDO2HPGDSLC6A2SLC6A4 | |
| SCHEMBL477349 | 1.00 | IDO1 (0.54) | IDO1TDO2HPGDSLC6A2SLC6A4 | |
| SCHEMBL10439949 | 0.98 | IDO1 (0.52) | IDO1TDO2HPGDSLC6A2SLC6A4 | |
| SCHEMBL1426754 | 0.89 | TSHR (0.50) | IDO1TDO2HPGDTSHR | |
| Diphenylmethanol SCHEMBL11366184 | 0.89 | MEN1 (0.45) | IDO1TDO2HPGDSLC6A2SLC6A4 | |
| SCHEMBL6075135 | 0.89 | CYP1A2 (0.65) | IDO1TDO2HPGDCNR2CYP1A2 | |
| SCHEMBL8671295 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRCA12CA1CA2 | |
| SCHEMBL6874895 | 0.85 | SLC6A2 (0.59) | IDO1TDO2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5161936 | 0.84 | SRD5A2 (0.55) | HPGDSMN1; SMN2TSHRMEN1KMT2A | |
| Diphenylmethanol SCHEMBL10868602 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2TSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563786-B2 | Method for producing optically active alcohol | MITSUI CHEMICALS, INC. (JP) | 2013-10-22 | — | — | US | disclosed |
| CN-102336723-B | Preparation method of L-chloperastine fendizoic acid | CHONGQING WORLD HAORUI PHARM CHEM CO LTD | 2013-06-12 | — | — | CN | disclosed |
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-04-12 | — | — | US | disclosed |
| EP-2412694-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | Mitsui Chemicals, Inc. (JP) | 2012-02-01 | — | — | EP | disclosed |
| CN-102336723-A | Preparation method of L-chloperastine fendizoic acid | CHONGQING WORLD HAORUI PHARM CHEM CO LTD | 2012-02-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | ADH1A, ADH1C, FHIT | IDO1 4327/4885TDO2 1885/4885HPGD 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.