SCHEMBL4775607

SCHEMBL4775607

CCCCCCCCc1csc(-c2ccsc2-c2cccs2)c1CCCCCCCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
GAA P10253 2/20 0.36
KDM4E B2RXH2 2/20 0.36
GPR35 Q9HC97 2/20 0.36
TYR P14679 1/20 0.34
ADK P55263 1/20 0.33
MAPT P10636 1/20 0.33
KEAP1 Q14145 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
CYSLTR2 Q9NS75 2/20 0.31
CYSLTR1 Q9Y271 2/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
LTA4H P09960 1/20 0.31
POLB P06746 1/20 0.31
PKM P14618 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5361367 1.00 ALDH1A1 (0.36) ALDH1A1GAAKDM4EGPR35TYR
SCHEMBL1043924 1.00 ALDH1A1 (0.36) ALDH1A1GAAKDM4EGPR35TYR
SCHEMBL1231112 0.99 ALDH1A1 (0.36) ALDH1A1GAAKDM4EGPR35TYR
SCHEMBL5085901 0.99 ALDH1A1 (0.36) ALDH1A1GAAKDM4EGPR35TYR
SCHEMBL587158 0.99 ALDH1A1 (0.36) ALDH1A1GAAKDM4EGPR35TYR
SCHEMBL1664821 0.99 ALDH1A1 (0.36) ALDH1A1GAAKDM4EGPR35TYR
SCHEMBL340368 0.91 KDM4E (0.41) ALDH1A1GAAKDM4EGPR35TYR
SCHEMBL4962707 0.91 KDM4E (0.41) ALDH1A1GAAKDM4EGPR35TYR
SCHEMBL30201661 0.90 ALDH1A1 (0.35) ALDH1A1GAAKDM4EGPR35TYR
SCHEMBL30265705 0.90 ALDH1A1 (0.35) ALDH1A1GAAKDM4EGPR35TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10815256-B2 Dithiophene compound, preparation and its application in organic photovoltaics thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2020-10-27 US disclosed
US-20190300554-A1 NOVEL DITHIOPHENE COMPOUND, PREPARATION AND ITS APPLICATION IN ORGANIC PHOTOVOLTAICS THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2019-10-03 US disclosed
WO-2018069935-A1 NOVEL DITHIOPHENE COMPOUND, PREPARATION AND ITS APPLICATION IN ORGANIC PHOTOVOLTAICS THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2018-04-19 WO disclosed
US-20080188670-A1 1,4-Dithienylbenzene Derivative NAT. INST. OF ADVANCED INDUSTRIAL SCI. AND TECH. (JP) 2008-08-07 US disclosed
EP-1943688-A1 LIQUID PHASE FABRICATION OF ACTIVE DEVICES INCLUDING ORGANIC SEMICONDUCTORS BASF SE (DE) 2008-07-16 EP disclosed
WO-2007039575-A1 LIQUID PHASE FABRICATION OF ACTIVE DEVICES INCLUDING ORGANIC SEMICONDUCTORS BASF SE (DE) 2007-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080188670-A1 1,4-Dithienylbenzene Derivative SLC22A4, SLC19A2, SLC22A1 ALDH1A1 890/4885GAA 4798/4885KDM4E 1985/4885
US-20190300554-A1 NOVEL DITHIOPHENE COMPOUND, PREPARATION AND ITS APPLICATION IN ORGANIC PHOTOVOLTAICS THEREOF DDT, TST, DIMT1 ALDH1A1 2643/4885GAA 4849/4885KDM4E 472/4885
US-10815256-B2 Dithiophene compound, preparation and its application in organic photovoltaics thereof DDT, TST, DIMT1 ALDH1A1 2923/4885GAA 4852/4885KDM4E 677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.