Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774510 | 0.94 | RAB9A (0.57) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| Trifluoroacetic Acid SCHEMBL4767186 | 0.90 | MAPT (0.46) | RAB9AMEN1KMT2AMAPTRXFP1 | |
| SCHEMBL4765391 | 0.83 | RXFP1 (0.51) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| Trifluoroacetic Acid SCHEMBL4772603 | 0.83 | SLC2A1 (0.50) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| Trifluoroacetic Acid SCHEMBL4775302 | 0.82 | MAPT (0.48) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4765332 | 0.82 | KMT2A (0.46) | KMT2AMAPTRXFP1SLC2A1HRH3 | |
| Trifluoroacetic Acid SCHEMBL4774281 | 0.81 | SLC2A1 (0.58) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4766836 | 0.81 | SLC2A1 (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL4770823 | 0.81 | SLC2A1 (0.47) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4768548 | 0.81 | ALDH1A1 (0.64) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | claimed |
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | HRH3, HRH4, HRH1 | RAB9A 2307/4885MEN1 2213/4885KMT2A 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.