Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.49 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807572 | 0.90 | TERT (0.66) | TERTTAAR1PDCD1LG2CD274TBXAS1 | |
| SCHEMBL369710 | 0.90 | TAAR1 (0.53) | TERTTAAR1TBXAS1FPR2ALOX15 | |
| SCHEMBL5355358 | 0.88 | TAAR1 (0.52) | TERTTAAR1TBXAS1FPR2ALOX15 | |
| SCHEMBL2474802 | 0.85 | TAAR1 (0.57) | TERTTAAR1TBXAS1FPR2ALOX15 | |
| SCHEMBL6638641 | 0.83 | TAAR1 (0.57) | TERTTAAR1PDCD1LG2CD274 | |
| SCHEMBL4985592 | 0.82 | TAAR1 (0.47) | TERTTAAR1TBXAS1FPR2ALOX15 | |
| SCHEMBL6225559 | 0.82 | TAAR1 (0.47) | TERTTAAR1PDCD1LG2CD274FPR2 | |
| SCHEMBL1971764 | 0.82 | TAAR1 (0.47) | TERTTAAR1TBXAS1FPR2ALOX15 | |
| SCHEMBL21290448 | 0.82 | TERT (0.58) | TERTTAAR1PDCD1LG2CD274TBXAS1 | |
| Ammonia Solution, Strong SCHEMBL28870904 | 0.81 | TAAR1 (0.46) | TERTTAAR1PDCD1LG2CD274TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961744-A1 | BASIC GROUP-CONTAINING COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-08-27 | — | — | EP | disclosed |