Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548145 | 0.76 | RET (0.46) | RETKDRCYP19A1MAOBADORA3 | |
| SCHEMBL69430 | 0.74 | PARP1 (0.48) | RETKDRCYP19A1MAOBADORA3 | |
| SCHEMBL1429502 | 0.74 | STK17B (0.46) | RETKDRCYP19A1MAOBADORA3 | |
| SCHEMBL69727 | 0.74 | RET (0.53) | RETKDRCYP19A1MAOBADORA3 | |
| SCHEMBL29441433 | 0.72 | MEN1 (0.52) | RETKDRCYP19A1MAOBADORA3 | |
| SCHEMBL28875665 | 0.72 | MEN1 (0.52) | RETKDRCYP19A1MAOBADORA3 | |
| SCHEMBL9837501 | 0.72 | RET (0.41) | RETKDRCYP19A1MAOBADORA3 | |
| SCHEMBL10513412 | 0.71 | STK17B (0.51) | RETKDRCYP19A1MAOBADORA3 | |
| SCHEMBL92288 | 0.71 | ESR1 (0.45) | RETKDRCYP19A1MAOBADORA3 | |
| SCHEMBL9434848 | 0.71 | ESR1 (0.45) | RETKDRCYP19A1MAOBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942556-A | Pyrimidinone compound and its application | 上海青煜医药科技有限公司 | 2019-06-28 | — | — | CN | disclosed |
| WO-2008084067-A2 | PHARMACEUTICALLY ACTIVE DIHYDROBENZOFURANE-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |
| EP-1874772-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108103-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2006-10-12 | — | — | WO | disclosed |