SCHEMBL477611

SCHEMBL477611

CCCCCC#CC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1399964 0.98 HMGCR (0.47)
SCHEMBL2395808 0.98 HMGCR (0.47)
SCHEMBL4130265 0.98 HMGCR (0.47)
SCHEMBL9625775 0.98 HMGCR (0.47)
SCHEMBL10892322 0.98 HMGCR (0.47)
SCHEMBL953772 0.92
SCHEMBL20471499 0.83 HMGCR (0.38)
SCHEMBL9626090 0.82 LMNA (0.40)
SCHEMBL9626655 0.82 LMNA (0.40)
SCHEMBL825898 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20230215723-A1 METHODS OF MANUFACTURING INTEGRATED CIRCUIT DEVICES USING CARBONYL COMPOUNDS ADEKA CORPORATION (JP) 2023-07-06 US claimed
CN-112079782-B Synephrine azole derivatives, and preparation method and application thereof 西南大学 2022-06-28 CN claimed
US-20220152587-A1 JUTE STEM-SUPPORTED PALLADIUM-NPS AND USE AS DIP-CATALYSTS FOR AQUEOUS TRANSFER HYDROGENATION KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-05-19 US claimed
CN-114478418-A Cinfeline sulfuryl tetrazole sulfonamide derivative, intermediate and application thereof 西南大学 2022-05-13 CN claimed
US-5993778-A RECEPTORS IN NEURONAL CELLS, INCLUDING METHODS FOR DETECTING PARTICULAR ODORANT LIGAND SPECIFICITY FOR PARTICULAR ODORANT RECEPTORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 1999-11-30 US claimed
US-20250325512-A1 Neurodegenerative Disorders And Muscle Diseases Implicating Pufas BIOJIVA LLC (US) 2025-10-23 US disclosed
US-12402638-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-09-02 US disclosed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US disclosed
EP-4531860-A1 PYRIMIDINONE COMPOUNDS FOR TREATING ACUTE INFLAMMATION Tes Pharma S.r.l. (IT) 2025-04-09 EP disclosed
US-12186317-B2 Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase TES PHARMA S.R.L. (IT) 2025-01-07 US disclosed
US-12156860-B2 Disorders implicating PUFA oxidation BIOJIVA LLC (US) 2024-12-03 US disclosed
WO-2024240882-A1 HETEROARYL AND HETEROCYCLIC COMPOUNDS FOR USE IN TREATING ACUTE INFLAMMATION TES PHARMA S.R.L. (IT) 2024-11-28 WO disclosed
WO-1997020846-A1 SUBSTITUTED PORPHYRINS BRUNEL UNIVERSITY (GB) 1997-06-12 WO disclosed
US-5500427-A ANGIOTENSIN II ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-03-19 US disclosed
EP-0588299-A2 1,2,4-Oxadiazolyl- or 1,2,4-thiadiazolyl-biphenyl derivatives as angiotensin II antagonists TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-03-23 EP disclosed
US-5113014-A PROCESSES FOR PREPARING PROSTAGLANDINS YALE UNIVERSITY (US) 1992-05-12 US disclosed
WO-1991009012-A1 PROCESSES FOR PREPARING PROSTAGLANDINS YALE UNIVERSITY (US) 1991-06-27 WO disclosed
US-4438277-A Hydronaphthalene derivatives SANKYO COMPANY, LIMITED (JP) 1984-03-20 US disclosed
US-4361515-A Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use SANKYO COMPANY, LIMITED (JP) 1982-11-30 US disclosed