SCHEMBL4130265

SCHEMBL4130265

CCCCCCCCC#CC=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 7/20 0.47
PTPN7 P35236 5/20 0.47
RECQL P46063 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
TSHR P16473 1/20 0.42
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
MCL1 Q07820 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
EPHX1 P07099 1/20 0.39
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1399964 1.00 HMGCR (0.47) HMGCRPTPN7RECQLTDP1TSHR
SCHEMBL2395808 1.00 HMGCR (0.47) HMGCRPTPN7RECQLTDP1TSHR
SCHEMBL9625775 1.00 HMGCR (0.47) HMGCRPTPN7RECQLTDP1TSHR
SCHEMBL10892322 1.00 HMGCR (0.47) HMGCRPTPN7RECQLTDP1TSHR
SCHEMBL477611 0.98
SCHEMBL953772 0.90
SCHEMBL20471499 0.85 HMGCR (0.38) HMGCRPTPN7RECQLTDP1ADH1B
SCHEMBL9626655 0.84 LMNA (0.40) HMGCRPTPN7RECQLTDP1ADH1B
SCHEMBL9626090 0.84 LMNA (0.40) HMGCRPTPN7RECQLTDP1ADH1B
SCHEMBL4169864 0.80 HMGCR (0.45) HMGCRPTPN7RECQLTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4509562-A1 COMPOSITION Sumitomo Chemical Company, Limited (JP) 2025-02-19 EP disclosed
EP-4456900-A1 RESPIRATORY STIMULANT PARENTERAL FORMULATIONS Enalare Therapeutics Inc. (US) 2024-11-06 EP disclosed
CN-118048210-A Detergent composition 广州立白企业集团有限公司 2024-05-17 CN disclosed
WO-2023129502-A1 RESPIRATORY STIMULANT PARENTERAL FORMULATIONS ENALARE THERAPEUTICS INC. (US) 2023-07-06 WO disclosed
CN-115803309-A Odorous compounds and methods of making the same 丝趣科尔卡有限公司 2023-03-14 CN disclosed
US-20090192153-A1 NOVEL ADENINE COMPOUND Dainippon Sumitomo Pharma Co., Ltd. a corporation of Japan (JP) 2009-07-30 US disclosed
US-20090118263-A1 Novel Adenine Compound DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2009-05-07 US disclosed
US-20090105212-A1 NOVEL ADENINE COMPOUND Dainippon Sumitomo Pharma Co., Ltd. a corporation of Japan (JP) 2009-04-23 US disclosed
US-20090099216-A1 NOVEL ADENINE COMPOUND ASTRAZENECA AKTIEBOLAG A CORPORATION OF SWEDEN (SE) 2009-04-16 US disclosed
US-20080269240-A1 Novel Adenine Compound Dainippon Sumitomo Pharma Co., Ltd. a corporation of Japan (JP) 2008-10-30 US disclosed
EP-1939198-A1 NOVEL ADENINE COMPOUND Dainippon Sumitomo Pharma Co., Ltd. (JP) 2008-07-02 EP disclosed
EP-1939199-A1 NOVEL ADENINE COMPOUND Dainippon Sumitomo Pharma Co., Ltd. (JP) 2008-07-02 EP disclosed
EP-1939200-A1 NOVEL ADENINE COMPOUND Dainippon Sumitomo Pharma Co., Ltd. (JP) 2008-07-02 EP disclosed
EP-1939202-A1 NOVEL ADENINE COMPOUND Dainippon Sumitomo Pharma Co., Ltd. (JP) 2008-07-02 EP disclosed
EP-1939201-A1 NOVEL ADENINE COMPOUND Dainippon Sumitomo Pharma Co., Ltd. (JP) 2008-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269240-A1 Novel Adenine Compound ADORA1, ADORA2A, ADORA3 HMGCR 1713/4885PTPN7 4745/4885RECQL 817/4885
US-20090118263-A1 Novel Adenine Compound ADORA1, ADORA2A, ADORA3 HMGCR 2453/4885PTPN7 4188/4885RECQL 1147/4885
US-20090099216-A1 NOVEL ADENINE COMPOUND ADORA1, CXCR6, NR0B1 HMGCR 2528/4885PTPN7 2716/4885RECQL 1093/4885
US-20090105212-A1 NOVEL ADENINE COMPOUND XDH, ADORA1, NUDT1 HMGCR 2447/4885PTPN7 3977/4885RECQL 1137/4885
US-20090192153-A1 NOVEL ADENINE COMPOUND ADORA1, SLC28A1, ADORA2A HMGCR 1873/4885PTPN7 4696/4885RECQL 1276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.