Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 6/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626655 | 1.00 | LMNA (0.40) | LMNAHMGCRPTPN7RECQLTDP1 | |
| SCHEMBL20471499 | 0.85 | HMGCR (0.38) | HMGCRPTPN7RECQLTDP1ADH1B | |
| SCHEMBL10892322 | 0.84 | HMGCR (0.47) | HMGCRPTPN7RECQLTDP1ADH1B | |
| SCHEMBL4130265 | 0.84 | HMGCR (0.47) | HMGCRPTPN7RECQLTDP1ADH1B | |
| SCHEMBL9625775 | 0.84 | HMGCR (0.47) | HMGCRPTPN7RECQLTDP1ADH1B | |
| SCHEMBL1399964 | 0.84 | HMGCR (0.47) | HMGCRPTPN7RECQLTDP1ADH1B | |
| SCHEMBL2395808 | 0.84 | HMGCR (0.47) | HMGCRPTPN7RECQLTDP1ADH1B | |
| SCHEMBL477611 | 0.82 | — | — | |
| Butane SCHEMBL11802511 | 0.77 | LMNA (0.44) | LMNAHMGCRPTPN7RECQLTDP1 | |
| SCHEMBL953772 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169033-B1 | INHIBITORS OF SLOW REACTING SUBSTANCE OF ANAPHYLAXIS | SCHERING CORPORATION (US) | 1992-02-12 | — | — | EP | disclosed |
| US-4988716-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1991-01-29 | — | — | US | disclosed |
| US-4798842-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |
| EP-0169033-A2 | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |