Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 9/20 | 0.35 |
| ▸ | NPC1 | O15118 | 7/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776116 | 1.00 | FASN (0.41) | FASNKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4795366 | 0.92 | FASN (0.42) | FASNKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4795361 | 0.92 | FASN (0.42) | FASNKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4781129 | 0.90 | FASN (0.42) | FASNKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4781136 | 0.90 | FASN (0.42) | FASNKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4147205 | 0.86 | PTGS1 (0.42) | FASNKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4147202 | 0.86 | PTGS1 (0.42) | FASNKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4776412 | 0.83 | APOBEC3A (0.32) | — | |
| SCHEMBL4776414 | 0.83 | APOBEC3A (0.32) | — | |
| SCHEMBL14043026 | 0.81 | RORC (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | claimed |
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | disclosed |