Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 9/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.57 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.55 |
| ▸ | PTGFR | P43088 | 3/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.54 |
| ▸ | PTGIR | P43119 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157606 | 0.86 | PTGER3 (0.73) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL28229070 | 0.83 | PTGER3 (0.42) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL28288349 | 0.82 | PTGER3 (0.56) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL27497043 | 0.81 | PTPN1 (0.46) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL9791289 | 0.78 | PTGER3 (0.56) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL9791294 | 0.78 | PTGER3 (0.56) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL2328371 | 0.78 | NFKB1 (0.50) | PTPN1 | |
| SCHEMBL28354000 | 0.76 | PTGER3 (0.53) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL29120112 | 0.76 | PTGER3 (0.50) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL4776134 | 0.76 | TBXAS1 (0.55) | PLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885352-A2 | COMBINATIONS COMPRISING JAK INHIBITORS AND AT LEAST ONE OF BCR-ABL, FLT-3, FAK OR RAF KINASE INHIBITORS | Novartis AG (US) | 2008-02-13 | — | — | EP | claimed |
| WO-2006056399-A2 | COMBINATIONS OF JAK INHIBITORS AND AT LEAST ONE OF BCR-ABL, FLT-3, FAK OR RAF KINASE INHIBITORS | NOVARTIS AG (CH) | 2006-06-01 | — | — | WO | claimed |
| CN-108962627-B | Organic system super capacitor or capacitance battery | 北京师范大学 | 2021-01-26 | — | — | CN | disclosed |
| CN-108963389-B | Gelable system for lithium-air battery and preparation method and application thereof | 北京师范大学 | 2020-11-13 | — | — | CN | disclosed |
| EP-1885352-A2 | COMBINATIONS COMPRISING JAK INHIBITORS AND AT LEAST ONE OF BCR-ABL, FLT-3, FAK OR RAF KINASE INHIBITORS | Novartis AG (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006056399-A2 | COMBINATIONS OF JAK INHIBITORS AND AT LEAST ONE OF BCR-ABL, FLT-3, FAK OR RAF KINASE INHIBITORS | NOVARTIS AG (CH) | 2006-06-01 | — | — | WO | disclosed |