Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 9/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.42 |
| ▸ | PTGFR | P43088 | 3/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.42 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.37 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776127 | 0.83 | PTGER3 (0.57) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL8415409 | 0.80 | PTPN1 (0.41) | PTGER3PTGER2PTGER4PTGER1EGFR | |
| SCHEMBL8415411 | 0.80 | PTPN1 (0.41) | PTGER3PTGER2PTGER4PTGER1EGFR | |
| SCHEMBL8837424 | 0.77 | CYP1A2 (0.38) | PTGER3PTGER2PTGER4PTGER1MEN1 | |
| SCHEMBL8837423 | 0.77 | CYP1A2 (0.38) | PTGER3PTGER2PTGER4PTGER1MEN1 | |
| Piperazine SCHEMBL8413610 | 0.73 | PDCD1 (0.39) | PTGER3PTGER2PTGER4PTGER1ALDH1A1 | |
| SCHEMBL7563015 | 0.73 | CD274 (0.37) | PTGER3PTGER2PTGER4PTGER1ALDH1A1 | |
| SCHEMBL8411325 | 0.72 | CD274 (0.38) | PTGER3PTGER2PTGER4PTGER1MEN1 | |
| SCHEMBL6528860 | 0.70 | F2R (0.44) | MAPTPTPN1LMNASMN1; SMN2 | |
| SCHEMBL8414403 | 0.70 | F2R (0.44) | MAPTPTPN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191740-A | Spirocyclopropane base oxidized indole compounds and preparation method thereof | 西华师范大学 | 2018-06-22 | — | — | CN | disclosed |