Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | RBP4 | P02753 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776650 | 0.92 | MC4R (0.44) | MC4RTSHRKDM4EPKMDPP4 | |
| SCHEMBL4776626 | 0.90 | MC4R (0.44) | MC4RTSHRKDM4EPKMDPP4 | |
| SCHEMBL4749130 | 0.89 | MC4R (0.44) | MC4RRBP4KMT2AMAPT | |
| SCHEMBL4749302 | 0.89 | MC4R (0.45) | MC4RRBP4KMT2ALMNA | |
| SCHEMBL4752862 | 0.84 | RAB9A (0.42) | MC4RRBP4LMNA | |
| SCHEMBL4752864 | 0.84 | RAB9A (0.42) | MC4RRBP4LMNA | |
| SCHEMBL4752863 | 0.84 | RAB9A (0.42) | MC4RRBP4LMNA | |
| SCHEMBL4751265 | 0.84 | RAB9A (0.42) | MC4RRBP4LMNA | |
| SCHEMBL4751666 | 0.84 | MC4R (0.43) | MC4RRBP4KMT2ANTRK1MEN1 | |
| SCHEMBL4752905 | 0.84 | MC4R (0.43) | MC4RRBP4KMT2ANTRK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |