Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.94 |
| ▸ | HTR7 | P34969 | 10/20 | 0.94 |
| ▸ | HTR2A | P28223 | 3/20 | 0.94 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.94 |
| ▸ | HTR2B | P41595 | 1/20 | 0.94 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.94 |
| ▸ | HTR2C | P28335 | 2/20 | 0.84 |
| ▸ | DRD2 | P14416 | 5/20 | 0.79 |
| ▸ | DRD4 | P21917 | 1/20 | 0.79 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.79 |
| ▸ | DRD3 | P35462 | 1/20 | 0.79 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.76 |
| ▸ | HTR6 | P50406 | 3/20 | 0.76 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388009 | 0.92 | HTR1A (0.86) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| SCHEMBL13944278 | 0.88 | HTR1A (0.78) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| SCHEMBL13944277 | 0.88 | HTR1A (0.78) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| SCHEMBL7463357 | 0.84 | HTR7 (0.70) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| SCHEMBL11867601 | 0.84 | HTR1A (0.70) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| Hydrochloric Acid SCHEMBL7468464 | 0.83 | HTR1A (0.69) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| Hydrochloric Acid SCHEMBL11866638 | 0.83 | HTR7 (0.69) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| SCHEMBL11676714 | 0.81 | HTR1A (0.64) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| SCHEMBL1383370 | 0.81 | HTR1A (0.72) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| SCHEMBL1382312 | 0.79 | HTR1A (1.00) | HTR1AHTR7HTR2ASLC6A4HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902044-A1 | 5-HTX MODULATORS | Bio Medisinsk Innovasjon AS (NO) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007007072-A1 | 5-HTX MODULATORS | BIO-MEDISINSK INNOVASJON AS (NO) | 2007-01-18 | — | — | WO | disclosed |