Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4770314 | 0.94 | HRH3 (0.52) | HRH3MEN1KMT2AATMCNR1 | |
| SCHEMBL4768212 | 0.88 | NPC1 (0.58) | HRH3MEN1KMT2AATMNPC1 | |
| SCHEMBL4774646 | 0.86 | HRH3 (0.67) | HRH3NPC1RAB9ATP53NFKB1 | |
| SCHEMBL4770633 | 0.84 | HRH3 (0.64) | HRH3MEN1KMT2ANPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL4770456 | 0.84 | NPC1 (0.52) | HRH3MEN1KMT2AATMNPC1 | |
| SCHEMBL4767370 | 0.82 | MEN1 (0.58) | HRH3MEN1KMT2AATMNPC1 | |
| SCHEMBL4770555 | 0.82 | NPC1 (0.51) | HRH3MEN1KMT2AATMNPC1 | |
| SCHEMBL4771157 | 0.81 | KMT2A (0.56) | HRH3MEN1KMT2ANPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL4765533 | 0.81 | HRH3 (0.61) | HRH3NPC1RAB9ATP53NFKB1 | |
| SCHEMBL4768583 | 0.81 | TMPRSS2 (0.62) | MEN1KMT2AATMCNR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |