Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777767 | 1.00 | SPHK2 (0.50) | SPHK2SPHK1KMT2ASMN1; SMN2POLB | |
| SCHEMBL4781614 | 0.86 | KCNH2 (0.48) | SPHK2SPHK1KMT2ASMN1; SMN2POLB | |
| SCHEMBL4781618 | 0.86 | KCNH2 (0.48) | SPHK2SPHK1KMT2ASMN1; SMN2POLB | |
| SCHEMBL4777088 | 0.83 | POLB (0.48) | KMT2ASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL4725427 | 0.83 | POLB (0.48) | KMT2ASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL4777083 | 0.83 | POLB (0.48) | KMT2ASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL4725421 | 0.83 | POLB (0.48) | KMT2ASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL3076592 | 0.80 | LMNA (0.44) | — | |
| SCHEMBL3076594 | 0.80 | LMNA (0.44) | — | |
| SCHEMBL4776192 | 0.80 | HSD17B2 (0.47) | KMT2APOLBHRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |