Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 3/20 | 0.39 |
| ▸ | MBTPS1 | Q14703 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887586 | 0.78 | GPR119 (0.53) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL9654218 | 0.76 | SLC6A4 (0.44) | SLC6A4KCNH2SLC6A2SLC6A3KMT2A | |
| SCHEMBL296666 | 0.75 | SLC6A4 (0.44) | SLC6A4KCNH2SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL14291229 | 0.74 | MCHR1 (0.56) | KMT2A | |
| SCHEMBL4725472 | 0.72 | ALDH1A1 (0.47) | SMYD3ALDH1A1KMT2AMEN1EGLN1 | |
| SCHEMBL4725477 | 0.72 | C5AR1 (0.43) | ALDH1A1KMT2AEGLN1 | |
| SCHEMBL14290711 | 0.72 | ALDH1A1 (0.51) | ALDH1A1KMT2AEGLN1 | |
| SCHEMBL4591868 | 0.71 | CNR1 (0.41) | SLC6A4KCNH2SLC6A2SLC6A3REN | |
| SCHEMBL4660108 | 0.69 | SLC6A4 (0.42) | SLC6A4KCNH2SLC6A2SLC6A3KMT2A | |
| SCHEMBL13434672 | 0.69 | REN (0.53) | SLC6A4SLC6A2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |