Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222692 | 1.00 | SCN9A (0.41) | SCN9AHTR1AHTR7PRMT5WDR77 | |
| SCHEMBL4725097 | 0.87 | DPP4 (0.42) | ABL1BCR | |
| SCHEMBL8211104 | 0.87 | DPP4 (0.42) | ABL1BCR | |
| SCHEMBL4795928 | 0.86 | HTR1A (0.39) | SCN9AHTR1AHTR7HTR6ALDH1A1 | |
| SCHEMBL4726619 | 0.84 | DAGLB (0.42) | HTR1AHTR7PRMT5WDR77CTSL | |
| SCHEMBL4726621 | 0.84 | DAGLB (0.42) | HTR1AHTR7PRMT5WDR77CTSL | |
| SCHEMBL4776087 | 0.82 | ROCK2 (0.42) | — | |
| SCHEMBL4776097 | 0.82 | ROCK2 (0.42) | — | |
| SCHEMBL4781769 | 0.80 | KDM4D (0.45) | SCN9AKDM4E | |
| SCHEMBL1797593 | 0.77 | CHRNB4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |