Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 6/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.69 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.69 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | HTR7 | P34969 | 1/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777691 | 1.00 | ADRA1D (0.69) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL12323178 | 0.91 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL14533980 | 0.87 | ADRA1D (0.58) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL10341260 | 0.86 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL10341259 | 0.86 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL4362747 | 0.85 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL34378 | 0.82 | ADRA1A (1.00) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL30361066 | 0.82 | ADRA1A (1.00) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL29363851 | 0.82 | ADRA1A (1.00) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| Tamsulosin SCHEMBL53998 | 0.82 | ADRA1A (1.00) | ADRA1DADRA1AADRA1BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329780-B2 | Method of preparing optically pure phenethylamine derivatives | CJ CORPORATION (KR) | 2008-02-12 | — | — | US | claimed |
| US-20070197828-A1 | Method of preparing optically pure phenethylamine derivatives | CJ CORPORATION (KR) | 2007-08-23 | — | — | US | claimed |
| WO-2007086074-A3 | A PROCESS FOR THE PREPARATION OF R (-) TAMSULOSIN HYDROCHLORIDE | USV LTD (IN) | 2008-05-02 | — | — | WO | disclosed |
| US-7329780-B2 | Method of preparing optically pure phenethylamine derivatives | CJ CORPORATION (KR) | 2008-02-12 | — | — | US | disclosed |
| EP-1692100-A4 | METHOD OF PREPARING OPTICALLY PURE PHENETHYLAMINE DERIVATIVES | CJ CORP (KR) | 2007-11-21 | — | — | EP | disclosed |
| US-20070197828-A1 | Method of preparing optically pure phenethylamine derivatives | CJ CORPORATION (KR) | 2007-08-23 | — | — | US | disclosed |
| WO-2007086074-A2 | A PROCESS FOR THE PREPARATION OF R (-) TAMSULOSIN HYDROCHLORIDE | USV LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007086074-A2 | A PROCESS FOR THE PREPARATION OF R (-) TAMSULOSIN HYDROCHLORIDE | USV LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |
| EP-1363878-B1 | PROCESS FOR PREPARING SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES | YONSUNG FINE CHEMICAL CO LTD (KR) | 2007-01-17 | — | — | EP | disclosed |
| EP-1692100-A1 | METHOD OF PREPARING OPTICALLY PURE PHENETHYLAMINE DERIVATIVES | CJ Corporation (KR) | 2006-08-23 | — | — | EP | disclosed |
| US-20060148046-A1 | Enzymatic process for the preparation of an intermediate compound and use thereof for the synthesis of tamsulosin hydrochloride | QUIMICA SINTETICA, S.A. | 2006-07-06 | — | — | US | disclosed |
| EP-1363878-A4 | PROCESS FOR PREPARING SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES | YONSUNG FINE CHEMICAL CO LTD (KR) | 2005-12-21 | — | — | EP | disclosed |
| US-6914159-B1 | Which have excellent therapeutic effects against hypertension, congestive heart failure, angina pectoris or prostatic hypertrophy higher yield; isolation step i.e. chromatography is not needed | YONSUNG FINE CHEMICAL CO., LTD. (KR) | 2005-07-05 | — | — | US | disclosed |
| WO-2005056521-A1 | METHOD OF PREPARING OPTICALLY PURE PHENETHYLAMINE DERIVATIVES | CJ CORPORATION (KR) | 2005-06-23 | — | — | WO | disclosed |
| EP-1363878-A1 | PROCESS FOR PREPARING SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES | Yonsung Fine Chemical Co. Ltd (KR) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002068382-A1 | PROCESS FOR PREPARING SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES | YONSUNG FINE CHEMICAL CO. LTD. (KR) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197828-A1 | Method of preparing optically pure phenethylamine derivatives | KMT2A, PNMT, PTMA | ADRA1D 92/4885ADRA1A 5/4885ADRA1B 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.