Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777639 | 0.81 | GAA (0.44) | MEN1KMT2ATP53MAPT | |
| SCHEMBL4836320 | 0.77 | P2RX7 (0.43) | — | |
| SCHEMBL4774945 | 0.70 | NAMPT (0.39) | — | |
| SCHEMBL4777390 | 0.69 | HTR2A (0.34) | MEN1KMT2APGRPYCR1MAPT | |
| SCHEMBL4767792 | 0.68 | MAPT (0.38) | MAPT | |
| SCHEMBL4793814 | 0.64 | P2RY14 (0.45) | MEN1KMT2AMAPT | |
| SCHEMBL4771116 | 0.63 | GAA (0.43) | MEN1KMT2ATP53ALOX5MAPT | |
| SCHEMBL4770634 | 0.63 | NPC1 (0.52) | MEN1KMT2AMAPT | |
| SCHEMBL4777345 | 0.61 | GAA (0.55) | MEN1KMT2ATP53MAPT | |
| SCHEMBL4769726 | 0.61 | POLB (0.44) | MEN1KMT2ATP53THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942888-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| WO-2007056078-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |