Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776096 | 0.82 | GAA (0.57) | NAMPTKCNA5GAALMNA | |
| SCHEMBL17591689 | 0.72 | LMNA (0.54) | KCNA5GAALMNAPDE4DTBXAS1 | |
| SCHEMBL4836320 | 0.72 | P2RX7 (0.43) | — | |
| SCHEMBL4777390 | 0.71 | HTR2A (0.34) | NAMPT | |
| SCHEMBL4777704 | 0.70 | MEN1 (0.34) | — | |
| SCHEMBL4770634 | 0.67 | NPC1 (0.52) | NAMPTGAALMNA | |
| SCHEMBL8319920 | 0.65 | PDE4D (0.48) | KCNA5GAALMNAPDE4DTBXAS1 | |
| SCHEMBL11990053 | 0.64 | TBXAS1 (0.63) | KCNA5LMNAPDE4DTBXAS1 | |
| SCHEMBL4531132 | 0.64 | CYP2C19 (0.48) | LMNA | |
| SCHEMBL28682706 | 0.63 | CYP2C19 (0.53) | LMNATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942888-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| WO-2007056078-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |