Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 16/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4831822 | 0.84 | GAA (0.47) | P2RX7CNR1 | |
| SCHEMBL4771136 | 0.79 | P2RX7 (0.42) | P2RX7CNR1 | |
| SCHEMBL4777704 | 0.77 | MEN1 (0.34) | — | |
| SCHEMBL4772351 | 0.77 | P2RX7 (0.43) | P2RX7 | |
| SCHEMBL4772423 | 0.76 | P2RX7 (0.41) | P2RX7 | |
| SCHEMBL4775019 | 0.74 | P2RX7 (0.41) | P2RX7CNR1 | |
| SCHEMBL4777514 | 0.74 | P2RX7 (0.42) | P2RX7CNR1CYP3A4 | |
| SCHEMBL4768267 | 0.73 | TRPM8 (0.40) | P2RX7 | |
| SCHEMBL4771252 | 0.73 | ALDH1A1 (0.47) | P2RX7 | |
| SCHEMBL4769705 | 0.73 | P2RX7 (0.43) | P2RX7CNR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942888-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| WO-2007056078-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |