Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287904 | 0.79 | KEAP1 (0.33) | KEAP1NFE2L2TSHRCES2CES1 | |
| SCHEMBL701478 | 0.79 | KEAP1 (0.33) | KEAP1NFE2L2TSHRCES2CES1 | |
| SCHEMBL7592777 | 0.79 | KEAP1 (0.33) | KEAP1NFE2L2TSHRCES2CES1 | |
| SCHEMBL237297 | 0.79 | KEAP1 (0.33) | KEAP1NFE2L2TSHRCES2CES1 | |
| SCHEMBL5576275 | 0.74 | TSHR (0.35) | KEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL66869 | 0.74 | KEAP1 (0.45) | KEAP1NFE2L2CHRM3TSHRCES2 | |
| SCHEMBL8846296 | 0.74 | KEAP1 (0.45) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL15151738 | 0.73 | EPHX1 (0.35) | KEAP1NFE2L2CHRM2CHRM1CYP2D6 | |
| SCHEMBL8502985 | 0.73 | LMNA (0.38) | KEAP1NFE2L2CHRM2CHRM1CYP2D6 | |
| SCHEMBL17313664 | 0.73 | KEAP1 (0.31) | KEAP1NFE2L2TSHRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661246-A | POLYESTER-BASED THERMAL SHRINKAGE FILM | SK化学株式会社 | 2017-05-10 | — | — | CN | disclosed |
| WO-2008015696-A2 | PROCESS FOR PREPARING CICLESONIDE | CADILA HEALTHCARE LIMITED (IN) | 2008-02-07 | — | — | WO | disclosed |