Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR5A | P47898 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 4/20 | 0.43 |
| ▸ | HTR1B | P28222 | 3/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538163 | 0.88 | NQO2 (0.58) | NQO2PKMPKLRSLC6A4MEN1 | |
| SCHEMBL2535250 | 0.86 | NQO2 (0.62) | NQO2PKMPKLRSLC6A4KMT2A | |
| SCHEMBL7367937 | 0.85 | NQO2 (0.61) | NQO2PKMPKLRSLC6A4KMT2A | |
| SCHEMBL3294986 | 0.80 | NQO2 (0.64) | NQO2PKMPKLRSLC6A4MEN1 | |
| SCHEMBL27929617 | 0.78 | NQO2 (0.61) | NQO2PKMPKLRMEN1KMT2A | |
| SCHEMBL4778984 | 0.78 | SLC6A4 (0.68) | SLC6A4HTR1AHTR2AHTR2CMPO | |
| SCHEMBL29507879 | 0.78 | PKM (0.63) | NQO2PKMPKLRSLC6A4MEN1 | |
| SCHEMBL396020 | 0.78 | PKM (0.63) | NQO2PKMPKLRSLC6A4MEN1 | |
| SCHEMBL11537110 | 0.76 | NQO2 (0.63) | NQO2PKMPKLRMEN1KMT2A | |
| SCHEMBL14574202 | 0.76 | GABRP (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581492-B1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2008-07-16 | — | — | EP | disclosed |