Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 9/20 | 0.71 |
| ▸ | CES1 | P23141 | 9/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693312 | 0.83 | CES2 (0.74) | CES2CES1ERN1CA1CA2 | |
| SCHEMBL6323127 | 0.82 | ERN1 (0.50) | CES2CES1ALDH1A1ALOX15ERN1 | |
| SCHEMBL7721943 | 0.81 | CES2 (0.49) | CES2CES1ALDH1A1ALOX15P2RX7 | |
| SCHEMBL1421628 | 0.81 | CES2 (0.71) | CES2CES1ALDH1A1ERN1CA1 | |
| SCHEMBL15273831 | 0.80 | CES2 (0.47) | CES2CES1ALDH1A1ALOX15ERN1 | |
| SCHEMBL29171310 | 0.80 | CES2 (0.47) | CES2CES1ALDH1A1ALOX15ERN1 | |
| SCHEMBL25390193 | 0.79 | CES2 (0.45) | CES2CES1ALDH1A1ALOX15CA1 | |
| SCHEMBL5948933 | 0.79 | CES2 (0.50) | CES2CES1ALDH1A1ALOX15CA1 | |
| SCHEMBL20560205 | 0.79 | CES2 (0.56) | CES2CES1P2RX7 | |
| SCHEMBL29467941 | 0.79 | CES2 (0.68) | CES2CES1ERN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108698982-B | Fluorine atom-containing compound and use thereof | 日产化学工业株式会社 | 2021-07-16 | — | — | CN | disclosed |
| EP-3404017-B1 | FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2020-05-13 | — | — | EP | disclosed |
| US-10590287-B2 | Charge-transporting varnish and organic electroluminescent element | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2020-03-17 | — | — | US | disclosed |
| EP-3252840-B1 | VARNISH FOR FORMATION OF CHARGE-TRANSPORTING THIN FILM | NISSAN CHEMICAL CORP (JP) | 2020-03-11 | — | — | EP | disclosed |
| EP-3309851-B1 | CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT | NISSAN CHEMICAL CORP (JP) | 2020-01-01 | — | — | EP | disclosed |
| CN-107710440-B | Charge-transporting varnish and organic electroluminescent element | 日产化学工业株式会社 | 2019-12-24 | — | — | CN | disclosed |
| CN-106132923-B | Oligoaniline derivative, charge-transporting varnish and organic electroluminescent device | 日产化学工业株式会社 | 2019-11-15 | — | — | CN | disclosed |
| CN-107210377-B | Varnish for forming charge-transporting thin film | 日产化学工业株式会社 | 2019-07-05 | — | — | CN | disclosed |
| US-10336686-B2 | Fluorine atom-containing compound and use thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2019-07-02 | — | — | US | disclosed |
| US-10301484-B2 | Varnish for formation of charge-transporting thin film | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2019-05-28 | — | — | US | disclosed |
| WO-2009002808-A2 | QUINAZOLINONE COMPOUNDS AND METHODS OF USE THEREOF | ARQULE, INC. (US) | 2008-12-31 | — | — | WO | disclosed |
| US-7402579-B2 | Quinobenzoxazine analogs and compositions | CYLENE PHARMACEUTICALS, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-7402579-B2 | Quinobenzoxazine analogs and compositions | CYLENE PHARMACEUTICALS, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-5942387-A | Combinatorial process for preparing substituted thiophene libraries | ELI LILLY AND COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0880558-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0825164-A2 | Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides | ELI LILLY AND COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1997026300-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10336686-B2 | Fluorine atom-containing compound and use thereof | ARF1, ARF5, ARFGAP1 | CES2 2869/4885CES1 4049/4885ALDH1A1 982/4885 |
| US-10590287-B2 | Charge-transporting varnish and organic electroluminescent element | SLCO4C1, SLCO2A1, SLC26A3 | CES2 398/4885CES1 1582/4885ALDH1A1 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.