⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190795 | 0.85 | TSHR (0.32) | — | |
| SCHEMBL376221 | 0.77 | MMP1 (0.33) | — | |
| SCHEMBL9634668 | 0.73 | MEN1 (0.36) | — | |
| SCHEMBL7075012 | 0.70 | LMNA (0.33) | — | |
| SCHEMBL27552870 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL11410484 | 0.67 | LMNA (0.34) | — | |
| SCHEMBL2981814 | 0.65 | LMNA (0.33) | — | |
| SCHEMBL3658365 | 0.65 | KMT2A (0.33) | — | |
| SCHEMBL6342988 | 0.65 | RAB9A (0.34) | — | |
| SCHEMBL1364158 | 0.64 | AKR1B1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6179658-A | — | — | None | — | — | JP | disclosed |
| US-20080131420-A1 | METHODS AND COMPOSITIONS FOR TREATING MUCOSAL INFLAMMATION | ACCENTIA, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| WO-2008008494-A2 | METHODS AND COMPOSITIONS FOR TREATING MUCOSAL INFLAMMATION | ACCENTIA BIOPHARMACEUTICALS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| EP-0744171-B1 | DENTAL COMPOSITION FOR HYPERSENSITIVE DENTIN | SUN MEDICAL CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0721773-B1 | Dental composition for relieving dentin hypersensitivity | SUN MEDICAL CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-5879663-A | Dental composition for dentin hypersensitivity | SUN MEDICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| US-5766328-A | Dental composition for relieving dentin hypersensitivity | SUN MEDICAL CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0744171-A1 | DENTAL COMPOSITION FOR HYPERSENSITIVE DENTIN | SUN MEDICAL CO., LTD. (JP) | 1996-11-27 | — | — | EP | disclosed |
| EP-0721773-A2 | Dental composition for relieving dentin hypersensitivity | SUN MEDICAL CO., LTD. (JP) | 1996-07-17 | — | — | EP | disclosed |
| JP-H06179658-A | PREPARATION OF METHYLOLHYDANTOIN WITH LOW FREE FORMALDEHYDE CONTENT AND COMPOSITION THEREOF | LONZA INC | 1994-06-28 | — | — | JP | disclosed |