Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777353 | 0.83 | MAOA (0.37) | IKBKBADORA2AADORA1KDM4EMEN1 | |
| SCHEMBL4771469 | 0.78 | TLR9 (0.33) | MEN1MAPTKMT2A | |
| SCHEMBL4775583 | 0.76 | PDE10A (0.35) | IKBKBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL4779519 | 0.66 | TLR9 (0.32) | — | |
| SCHEMBL27438188 | 0.61 | ALOX5 (0.47) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15769819 | 0.60 | KDM4E (0.46) | IKBKBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL10097345 | 0.60 | MAOA (0.50) | ADORA1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL28819042 | 0.59 | ESR2 (0.60) | ADORA2AADORA1KDM4EMEN1ALDH1A1 | |
| SCHEMBL1360896 | 0.59 | KDM4E (0.47) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| Benzidine SCHEMBL29155805 | 0.56 | CYP3A4 (0.65) | MEN1ALDH1A1MAPTKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984332-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |