Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779519 | 0.89 | TLR9 (0.32) | TLR9 | |
| SCHEMBL4777353 | 0.88 | MAOA (0.37) | TLR9MAPTSQORMEN1USP2 | |
| SCHEMBL4775583 | 0.85 | PDE10A (0.35) | MAPTMEN1KMT2A | |
| SCHEMBL4778609 | 0.78 | IKBKB (0.33) | MAPTMEN1KMT2A | |
| SCHEMBL4779526 | 0.77 | — | — | |
| SCHEMBL4780752 | 0.69 | NPC1 (0.44) | MAPT | |
| SCHEMBL10097345 | 0.68 | MAOA (0.50) | MAPTMEN1USP2KMT2A | |
| SCHEMBL2884180 | 0.63 | CYP11B2 (0.37) | MAPTMEN1KMT2A | |
| SCHEMBL2881706 | 0.62 | HRH3 (0.36) | MAPTMEN1KMT2A | |
| SCHEMBL4779864 | 0.60 | NOX1 (0.41) | MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984332-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |