Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768505 | 0.91 | PTGDR2 (0.53) | PTGDR2CYP1A2CYP2C19KLKB1KLK1 | |
| SCHEMBL4777221 | 0.89 | PTGDR2 (0.70) | PTGDR2CYP1A2CYP2C19KLKB1KLK1 | |
| SCHEMBL27768408 | 0.85 | PTGDR2 (0.52) | PTGDR2CYP1A2CYP2C19KLKB1KLK1 | |
| SCHEMBL27789966 | 0.85 | PTGDR2 (0.56) | PTGDR2CYP1A2CYP2C19KLKB1KLK1 | |
| SCHEMBL27790170 | 0.84 | PTGDR2 (0.50) | PTGDR2CYP1A2CYP2C19KLKB1KLK1 | |
| SCHEMBL27905712 | 0.83 | PTGDR2 (0.49) | PTGDR2CYP1A2CYP2C19KLKB1KLK1 | |
| SCHEMBL27768501 | 0.83 | PTGDR2 (0.56) | PTGDR2CYP1A2CYP2C19KLKB1KLK1 | |
| SCHEMBL2000681 | 0.82 | PTGDR2 (0.79) | PTGDR2AKR1B1 | |
| SCHEMBL2007317 | 0.74 | PTGDR2 (0.73) | PTGDR2CYP1A2CYP2C19AKR1B1KDM4E | |
| SCHEMBL2010037 | 0.73 | PTGDR2 (0.72) | PTGDR2CYP1A2CYP2C19KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |
| EP-1931632-A2 | USEFUL INDOLE COMPOUNDS | Microbia Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007022501-A2 | USEFUL INDOLE COMPOUNDS | MICROBIA, INC. (US) | 2007-02-22 | — | — | WO | disclosed |