Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927234 | 0.98 | HRH3 (0.43) | HRH3HRH4ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4780502 | 0.83 | HRH3 (0.47) | HRH3ALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL7678459 | 0.81 | MC4R (0.46) | HRH3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3302046 | 0.67 | CHKA (0.32) | ALDH1A1KDM4EL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL10680312 | 0.67 | HRH3 (0.48) | HRH3HRH4ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL3651286 | 0.67 | — | — | |
| SCHEMBL844842 | 0.65 | HRH3 (0.47) | HRH3HRH4ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4277270 | 0.65 | HRH3 (1.00) | HRH3HRH4ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL11329325 | 0.64 | ALDH1A1 (0.62) | HRH3HRH4ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1854026 | 0.63 | CYP2C19 (0.46) | HRH3HRH4ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214823-A2 | Alkylamide derivatives with H2-receptor antagonistic and cytoprotective action | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1987-03-18 | — | — | EP | claimed |
| JP-62153279-A | — | — | None | — | — | JP | disclosed |
| WO-2008001134-A1 | 1,2,3,8,9,9A-HEXAHYDRO-7H-BENZO(DE)-1,7-NAPHTHYRIDIN-7-ONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2008-01-03 | — | — | WO | disclosed |
| US-4837316-A | ANTIULCER AGENTS | FUJIREBIO KABUSHIKI KAISHA (JP) | 1989-06-06 | — | — | US | disclosed |
| JP-S62153279-A | SUBSTITUTED PHENOXYPROPYLAMIDE DERIVATIVE AND PRODUCTION THEREOF | FUJIREBIO INC | 1987-07-08 | — | — | JP | disclosed |
| EP-0214823-A2 | Alkylamide derivatives with H2-receptor antagonistic and cytoprotective action | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1987-03-18 | — | — | EP | disclosed |