Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776051 | 0.84 | CACNA1G (0.46) | HSP90AB1MAPTCACNA1GALDH1A1MEN1 | |
| SCHEMBL4887895 | 0.80 | CHRM4 (0.40) | HSP90AB1MAPTCACNA1GKDM4EALDH1A1 | |
| SCHEMBL4777936 | 0.78 | PTGS1 (0.42) | HSP90AB1MAPTCACNA1GALDH1A1PPARD | |
| SCHEMBL1228985 | 0.77 | CASR (0.40) | ALDH1A1 | |
| SCHEMBL19095368 | 0.77 | MAPT (0.47) | HSP90AB1MAPTCACNA1GALDH1A1MEN1 | |
| SCHEMBL17432438 | 0.71 | PPARD (0.49) | MAPTCACNA1GKDM4EALDH1A1MEN1 | |
| SCHEMBL19538665 | 0.70 | TSHR (0.68) | MAPTKDM4EALDH1A1KMT2APPARD | |
| SCHEMBL19095372 | 0.69 | ALDH1A1 (0.43) | HSP90AB1MAPTCACNA1GKDM4EALDH1A1 | |
| SCHEMBL1228844 | 0.68 | CASR (0.37) | ALDH1A1 | |
| SCHEMBL22963896 | 0.68 | HRH3 (0.58) | PPARDPPARACHRM4KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984369-A2 | NITROIMIDAZOLE COMPOUNDS | Novartis AG (CH) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007075872-A2 | NITROIMIDAZOLE COMPOUNDS | NOVARTIS AG (CH) | 2007-07-05 | — | — | WO | disclosed |